

Metoject is a pre-filled syringe for injection, containing the drug methotrexate. Metoject is registered for the treatment of rheumatoid arthritis and is available in five different doses. Your doctor will choose the correct dose for you.
The active ingredient of Metoject is methotrexate (MTX). Methotrexate is a very well-known disease modifying antirheumatic drug (DMARD). It relieves the pain associated with joint inflamation and/or psoriasis and helps to prevent this inflamation. Methotrexate also helps prevent joint damage which can occure from RA. In these autoimmune diseases, the immune system is too active and mistakenly attacks the own body. Methotrexate can help to slow down the effects of an over-stimulated immune system and thus to control disease activity.
The patient information leaflet is at first quite frightening as methotrexate belongs to the drug class of cytostatic agents. Methotrexate is also used in cancer therapy in much higher doses than in the treatment of inflammatory rheumatic diseases. Side effects are possible with low-dose methotrexate, but they occur less often and are less severe than in the treatment with higher doses. Furthermore, there are several possibilities to reduce these discomforts. Therefore, should you have any side effect while taking the drug, please inform your doctor.
Metoject is only available on a prescription and must be used carefully. Unlike many drugs, methotrexate is only used once a week when taken for rheumatoid arthritis.